Mouse Leukocyte Surface Antigen CD53 (CD53) Protein
1235€ (100 µg)
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935106861
info@markelab.com
name
Mouse Leukocyte Surface Antigen CD53 (CD53) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693423
tested applications
SDS-PAGE
Description
Mouse CD53 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse CD53 (Q61451) (Glu107-Asn181) was expressed with a polyhistidine tag at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD53 |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 10.6 kDa Sequence Fragment: Glu107-Asn181 Tag: N-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q61451 |
| Alias | MOX44,TSPAN25,Leukocyte surface antigen CD53,Cell surface glycoprotein CD53,Tetraspanin-25 |
| Background | Protein CD53 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD53 is a cell surface glycoprotein and a member of the tetraspanin superfamily, which plays a critical role in immune cell function. It is expressed primarily on hematopoietic cells, including leukocytes such as T cells, B cells, monocytes, neutrophils, and natural killer (NK) cells. CD53 is involved in immune cell signaling, adhesion, and trafficking, making it an important molecule for maintaining immune system integrity and function. CD53's role in facilitating interactions between immune cells and in transducing signals that promote activation and differentiation makes it a key participant in the regulation of immune responses. The tetraspanins, of which CD53 is a member, are integral membrane proteins that form complexes with other membrane proteins, including integrins, growth factor receptors, and immune receptors. CD53 is known to associate with other tetraspanins and create specialized membrane domains called tetraspanin-enriched microdomains (TEMs), which function in organizing membrane proteins and coordinating signaling pathways. The protein has been implicated in the immune system’s defense against pathogens and in the activation and function of leukocytes.
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