Mouse Leukemia Inhibitory Factor Receptor Alpha (LIFR) ELISA Kit
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935106861
info@markelab.com
Precio
562.5€ (96 tests)
Elisa Kits LIFR
proveedor
Abbexareference
abx254244Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Leukemia Inhibitory Factor Receptor Alpha (LIFR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse LIFR concentrations in serum, plasma and other biological fluids.
Background
The leukemia inhibitory factor receptor (LIFR), also known as the LIF receptor subunit alpha, is a component of a cytokine receptor complex responsible for mediating the effects of the leukemia inhibitory factor (LIF). LIF is part of the interleukin-6 (IL-6) family of cytokines and is involved in various cellular processes, such as cell survival, proliferation, and differentiation, particularly in neuronal, hematopoietic, and reproductive cells. LIFR is encoded by the LIFR gene, located on chromosome 5p13, and is widely expressed across various tissues, including the placenta, brain, liver, and bone marrow. LIFR functions as a non-signaling receptor subunit and, upon binding to LIF, associates with the co-receptor gp130. Together, this receptor complex initiates intracellular signaling pathways that are central to immune responses, tissue repair, and neural development. LIFR is significant in embryonic development and stem cell maintenance, and dysregulation of LIFR signaling is associated with several diseases, such as inflammatory disorders, cancer, and neurodegenerative diseases.
Características del producto
category
ELISA Kits
immunogen target
Leukemia Inhibitory Factor Receptor Alpha (LIFR)
reactivity
Mouse
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Other biological fluids
size 1
96 tests
alias
Leukemia inhibitory factor receptor,SWS,SJS2,STWS,CD118,LIF-R,LIF receptor
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LIFR
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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