Mouse Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Protein

Este producto es parte de HAVCR1 - hepatitis A virus cellular receptor 1
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195€ (10 µg)

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935106861
info@markelab.com
name
Mouse Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067644
tested applications
WB, SDS-PAGE

Description

Recombinant KIM-1 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Hepatitis A Virus Cellular Receptor 1 (HAVCR1)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 24.9 kDa  Observed MW (SDS-PAGE): 32 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Tyr22-Gly237
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q5QNS5
Alias
Kidney injury molecule 1,TIM,KIM1,TIM1,CD365,HAVCR,KIM-1,TIM-1,TIMD1,TIMD-1,HAVCR-1,T-cell immunoglobulin and mucin domain-containing protein 1,T-cell immunoglobulin mucin receptor 1,T-cell membrane protein 1
Background
Protein HAVCR1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Hepatitis A Virus Cellular Receptor 1 (HAVCR1), also known as TIM-1 (T-cell immunoglobulin and mucin domain-containing protein 1), is a receptor protein expressed primarily on the surface of kidney epithelial cells and various immune cells. It is a member of the TIM family of proteins, which includes other receptors like TIM-3 and TIM-4. HAVCR1 plays a critical role in immune regulation, cell signaling, and disease pathogenesis, particularly within inflammatory and immune-mediated conditions. Initially identified as the receptor for hepatitis A virus (HAV), HAVCR1 has since been associated with numerous physiological and pathological processes, including immune cell activation, tissue inflammation, and the regulation of T-cell responses. HAVCR1 is implicated in immune tolerance and modulation of immune responses, making it relevant in autoimmune disorders, infections, and cancer.

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