Mouse Interleukin 3 Receptor alpha (IL3RA) ELISA Kit

Este producto es parte de IL3RA - interleukin 3 receptor subunit alpha
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Interleukin 3 Receptor alpha (IL3RA) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx521054
tested applications
ELISA

Description

Mouse Interleukin 3 Receptor alpha (IL3RA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Interleukin 3 Receptor alpha (IL3RA) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Interleukin 3 Receptor alpha (IL3RA)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
31.2 pg/ml - 2000 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P26952
Alias
IL-3 receptor subunit alpha,IL3R,CD123,IL3RX,IL3RY,IL3RAY,hIL-3Ra,IL-3R-alpha,
Background
Elisa kits for IL3RA
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

IL3RA, also known as CD123, encodes the alpha subunit of the interleukin-3 (IL-3) receptor, an essential receptor in hematopoiesis and immune cell regulation. IL3RA pairs with the common beta subunit (CSF2RB or IL3RB) to form the functional receptor complex for IL-3, a cytokine primarily involved in the growth, differentiation, and survival of various blood cell lineages. The IL-3 receptor is primarily expressed on hematopoietic progenitor cells and is particularly prominent on cells within the myeloid lineage, including basophils, eosinophils, and certain dendritic cells. IL3RA’s role in hematopoiesis is critical as it contributes to regulating immune responses by driving differentiation and survival of blood cell progenitors. The receptor is also crucial in mobilizing immune cells, promoting proliferation and enhancing responses to infection. IL3RA’s clinical significance has grown in recent years, with elevated expression observed in leukemias, particularly in acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm (BPDCN). Its surface expression profile has made IL3RA an important therapeutic target, especially in cancers where IL3RA-positive cells drive disease progression.

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