Mouse Interleukin 3 (IL3) Protein

Este producto es parte de IL3 - interleukin 3
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247€ (10 µg)

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935106861
info@markelab.com
name
Mouse Interleukin 3 (IL3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069741
tested applications
WB, SDS-PAGE

Description

Mouse IL3 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetInterleukin 3 (IL3)
HostE. coli
OriginMouse
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 45.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp33-Cys166 Tag: N-terminal His tag
ExpressionRecombinant
Purity> 90%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP01586
AliasIL-3,MCG, MULTI-CSF,Hematopoietic growth factor,Mast cell growth factor,MCGF,Multipotential colony-stimulating factor,P-cell-stimulating factor
BackgroundProtein IL3
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin-3 (IL3) is a cytokine, a type of signaling protein involved in regulating immune and hematopoietic (blood cell formation) responses. Cytokines are crucial to the communication between cells, particularly within the immune system, helping to modulate the body's responses to pathogens, trauma, and inflammation. IL-3 is produced primarily by activated T cells, but also by other cells including mast cells, eosinophils, and monocytes, especially in response to immune challenges. Its primary function is to regulate the growth, differentiation, and survival of pluripotent hematopoietic stem cells, as well as various lineages of blood cells, making it a key player in hematopoiesis (the formation of blood cellular components). IL-3 is important not only in normal immune responses but also in pathological conditions such as allergies, autoimmune disorders, and cancers. The signaling cascade initiated by IL-3 involves several pathways, including the JAK/STAT (Janus kinase/Signal transducers and activators of transcription) and PI3K (Phosphoinositide 3-kinase)/AKT pathways, which contribute to the proliferation and survival of various cell types

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