Mouse Interleukin 2 Receptor Alpha (IL2RA) Protein

Este producto es parte de IL2RA - interleukin 2 receptor subunit alpha
Mouse Interleukin 2 Receptor Alpha (IL2RA) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein IL2RA

proveedor

Abbexa

reference

abx067496

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse Interleukin 2 Receptor Alpha (IL2Ra) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Interleukin 2 receptor subunit alpha (IL2RA), also known as CD25, is a crucial component of the high-affinity interleukin-2 (IL-2) receptor complex, which is essential for regulating immune responses, particularly T-cell proliferation and survival. The IL-2 receptor plays a pivotal role in both adaptive immunity and immune tolerance, with IL2RA being one of the three subunits that form the IL-2 receptor complex. The IL-2 receptor system is critically involved in the regulation of T-cell homeostasis, immune activation, and the suppression of autoimmunity. IL2RA is primarily expressed on activated T cells, particularly regulatory T cells (Tregs), which are crucial for maintaining immune tolerance. It is also found on other immune cells, including activated B cells, dendritic cells, and natural killer (NK) cells under certain conditions. Importantly, IL2RA expression is tightly regulated, being upregulated upon T-cell activation and playing a central role in fine-tuning immune responses.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Interleukin 2 Receptor Alpha (IL2RA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 31.2 kDa Observed MW: 32 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu22-Tyr235 Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL2RA


dry ice

No


availability

Shipped within 5-7 working days.


alias

p55,CD25,IL2R,IMD41,TCGFR,IDDM10,Interleukin-2 receptor subunit alpha,IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA,TAC antigen


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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ELISA, WB

reactivity

human,mouse,rat

status

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clonality

polyclonal

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