Mouse Interleukin 19 (IL19) CLIA Kit

Mouse Interleukin 19 (IL19) CLIA Kit es un kit CLIA tipo Sandwich para su uso con suero, plasma, homogeneizados de tejido, lisados de células, sobrenadantes de cultivos celulares y otros fluidos biológicos.

Background

Interleukin 19 (IL19) is a member of the IL-10 cytokine family, which includes other related cytokines such as IL-20, IL-22, IL-24, and IL-26. The IL-10 family plays key roles in immune regulation, inflammation, and tissue homeostasis. IL-19 was identified for its ability to influence immune responses and is involved in promoting anti-inflammatory effects and tissue repair processes, while also playing a role in the pathology of certain autoimmune and inflammatory diseases. IL-19 is primarily produced by monocytes, macrophages, keratinocytes, and other epithelial cells in response to pro-inflammatory stimuli such as lipopolysaccharides (LPS), IL-1β, and TNF-α. It is classified as a pro-inflammatory cytokine, but it exhibits immunoregulatory functions, particularly in the context of chronic inflammation. IL-19 acts through the IL-20 receptor complex, which consists of the IL-20R1 and IL-20R2 subunits, and triggers downstream signaling pathways, including the JAK-STAT pathway, to modulate the expression of various inflammatory mediators.