Mouse Interleukin 11 (IL11) Protein

234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Interleukin 11 (IL11) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167415
tested applications
WB, SDS-PAGE
Description
Interleukin 11 Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Interleukin 11 (IL11) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 22.6 kDa Observed MW (SDS-PAGE): 23 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro25-Leu199 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 97% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | AGIF,IL-11,Adipogenesis inhibitory factor,Oprelvekin |
Background | Protein IL11 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-11 (IL11) is a member of the IL-6-type cytokine family, which plays crucial roles in regulating immune responses, inflammation, and hematopoiesis. IL-11 was first identified for its role in promoting the proliferation of hematopoietic stem cells and megakaryocytes, which are essential for platelet production. Since then, IL-11 has been implicated in various biological processes, including tissue regeneration, bone remodeling, and immune system regulation. IL-11 signals through its specific receptor complex, initiating various downstream signaling cascades, primarily through the JAK/STAT pathway. IL-11 is mainly secreted by stromal cells, fibroblasts, and epithelial cells in response to various stimuli, including inflammatory signals. While initially considered a supportive cytokine in hematopoiesis, more recent studies have shown that IL-11 plays a significant role in tissue fibrosis, chronic inflammation, and even cancer progression
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