Mouse Interferon Gamma (IFNG) Protein
416€ (20 µg)
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name
Mouse Interferon Gamma (IFNG) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx670288
tested applications
ELISA, WB
Description
Mouse Interferon Gamma (IFNG) Protein is a Recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interferon Gamma (IFNG) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Size 1 | 20 µg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: Phosphate buffered saline |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C after reconstitution. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01580 |
| Alias | IFG,IFI,IMD69,IFN-gamma,Immune interferon |
| Background | Protein IFNG |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interferon Gamma (IFNG) is a pivotal cytokine of the immune system, classified as a type II interferon, and is primarily produced by activated T lymphocytes, natural killer (NK) cells, and NKT cells. Unlike type I interferons, IFNG signals through a distinct receptor, the interferon gamma receptor (IFNGR), leading to the activation of the JAK-STAT pathway and the induction of a unique set of genes critical for immune defense. IFNG plays a central role in coordinating both innate and adaptive immune responses, including macrophage activation for enhanced phagocytosis and antigen processing, upregulation of MHC class I and II molecules to improve antigen presentation, and stimulation of cytotoxic T cells. It is also essential in granuloma formation to contain intracellular pathogens, such as Mycobacterium tuberculosis. Dysregulation of IFNG activity is implicated in various inflammatory and autoimmune conditions, as well as chronic infections. Its therapeutic potential in immunotherapy and as a biomarker in certain cancers and infectious diseases remains an active focus of study.
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