Mouse Intercellular Adhesion Molecule 4 (ICAM4) CLIA Kit

Este producto es parte de ICAM4 - intercellular adhesion molecule 4
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845€ (96 tests)

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935106861
info@markelab.com
name
Mouse Intercellular Adhesion Molecule 4 (ICAM4) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492875
tested applications
CLIA

Description

Mouse Intercellular Adhesion Molecule 4 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
CLIA Kits
Immunogen Target
Intercellular Adhesion Molecule 4 (ICAM4)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.059 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Landsteiner-Wiener blood group,LW,CD242,Landsteiner-Wiener blood group glycoprotein
Background
CLIA Kits ICAM4
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ICAM4 (Intercellular Adhesion Molecule 4) is a transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily and is primarily expressed on erythrocytes (red blood cells). ICAM4 functions as an adhesion molecule, playing a significant role in cell-to-cell interactions, particularly between red blood cells and other cell types. It is also known as the Landsteiner-Wiener blood group antigen and is encoded by the ICAM4 gene, which is located on chromosome 19. The primary physiological role of ICAM4 is in mediating interactions with other cells, notably endothelial cells, leukocytes, and macrophages, contributing to the cellular processes in circulation and immune response. ICAM4 is part of the ICAM family of molecules, which includes ICAM1, ICAM2, ICAM3, and ICAM5. ICAM molecules are generally involved in leukocyte-endothelial cell adhesion and signaling pathways that regulate inflammation and immune responses. ICAM4, although sharing structural similarities with these other molecules, is unique in its specificity to erythrocytes and its function in erythrocyte interactions, notably through binding with integrins such as α4β1 and αV integrins found on various immune cells.

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