Mouse Intelectin 1 (ITLN1) Protein
234€ (10 µg)
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935106861
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name
Mouse Intelectin 1 (ITLN1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067296
tested applications
WB, SDS-PAGE
Description
Mouse ITLN1 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Intelectin 1 (ITLN1) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 28.7 kDa Observed MW (SDS-PAGE): 30 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg28-Gly270 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O88310 |
| Alias | HL1,LFR,HL-1,INTL,ITLN,hIntL,omentin |
| Background | Protein ITLN1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ITLN1 is a secreted glycoprotein mainly expressed in adipose tissue, the small intestine, and the mesothelial cells It is known for its role in immune defense by binding to pathogen-associated carbohydrate structures, such as galactofuranose residues on microbial surfaces ITLN1 also acts as an adipokine, influencing insulin sensitivity and glucose metabolism through its association with obesity and metabolic diseases Decreased ITLN1 levels are linked to insulin resistance, type 2 diabetes, and obesity, while elevated levels are observed under conditions like calorie restriction or weight loss ITLN1 exerts anti-inflammatory and anti-oxidative effects, improving metabolic function by reducing inflammatory cytokine production and enhancing insulin signaling in skeletal muscle It is also involved in tissue repair and epithelial protection through its interaction with epithelial cell surfaces Dysregulation of ITLN1 expression is associated with cardiovascular diseases and inflammatory disorders, making it a potential therapeutic target for obesity-related metabolic dysfunction
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