935106861
info@markelab.com
Precio
556.25€ (96 tests)
Mouse Mouse Integrin Beta III / CD61 (ITGB3) ELISA Kit (Integrin Beta III / CD61) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Integrin Beta III / CD61 (ITGB3) concentrations in tissue homogenates, cell lysates and other biological fluids.
ITGB3 (Integrin Subunit Beta 3) encodes the β3 subunit of integrins, which are transmembrane receptors that mediate cell-cell and cell-extracellular matrix (ECM) interactions. Integrins are essential in diverse cellular processes, including cell adhesion, migration, signal transduction, immune responses, and angiogenesis. The ITGB3 protein partners with αIIb (encoded by ITGA2B) and αV (encoded by ITGAV) to form αIIbβ3 and αVβ3 integrins, respectively. These heterodimers are pivotal for platelet aggregation, thrombosis, wound healing, and interactions with extracellular matrix proteins like fibrinogen, fibronectin, and vitronectin. ITGB3 is expressed in platelets, endothelial cells, and various tissues involved in cell movement and immune responses. Dysregulation or mutation of ITGB3 can lead to disorders such as Glanzmann thrombasthenia, affecting platelet function, or it can play a role in pathological conditions like cancer metastasis, where altered cell adhesion and migration are key.
ELISA Kits
Integrin Beta III / CD61 (ITGB3)
Mouse
31.2 pg/ml - 2000 pg/ml
18.8 pg/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
GT,GT2,CD61,GP3A,BDPLT2,GPIIIa,BDPLT16,BDPLT24,Integrin beta-3,Platelet membrane glycoprotein IIIa
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ITGB3
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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