Mouse Integrin beta-4 (ITGB4) ELISA Kit

Este producto es parte de ITGB4 - integrin subunit beta 4
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Integrin beta-4 (ITGB4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528825
tested applications
ELISA

Description

Mouse Integrin beta-4 (ITGB4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Integrin beta-4 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Integrin beta-4 (ITGB4)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
A2A863
Gene ID
192897
Alias
Integrin beta-4,CD104,GP150,JEB5A,JEB5B
Background
Elisa kits for ITGB4
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Integrin subunit beta 4 (ITGB4) is a vital cell-adhesion molecule in the integrin family, specifically expressed in epithelial cells, where it plays a critical role in cell adhesion, signal transduction, and cellular responses to external stimuli. ITGB4 is notable for its involvement in forming hemidesmosomes, specialized structures that attach epithelial cells to the basement membrane, thereby contributing to tissue integrity, resilience, and structural stability. ITGB4 often pairs with the alpha 6 integrin subunit (forming the α6β4 integrin complex), allowing these integrins to specifically interact with laminins in the extracellular matrix. These interactions mediate a variety of essential biological processes, including cell adhesion, migration, differentiation, and survival. Due to its essential role in maintaining epithelial tissue structure and regulating cellular signaling, dysregulation or mutations in ITGB4 have been associated with a range of disorders, including epidermolysis bullosa and certain cancers.

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