Mouse Integrin Beta 2 (ITGB2) ELISA Kit

715€ (96 tests)
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name
Mouse Integrin Beta 2 (ITGB2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx512307
tested applications
ELISA
Description
Mouse Integrin Beta 2 (ITGB2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Integrin Beta 2 (ITGB2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | Integrin Beta 2 (ITGB2) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.78 ng/ml - 50 ng/ml |
Sensitivity | < 0.404 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | P11835 |
Alias | LAD,CD18,MF17,MFI7,LCAMB,LFA-1,MAC-1,Integrin beta-2,Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta |
Background | Elisa kits for ITGB2 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ITGB2, or integrin subunit beta 2, is a protein that plays a central role in leukocyte adhesion and signaling, facilitating the immune system's response to infections and inflammation. ITGB2, also known as CD18, is part of the integrin family, which consists of transmembrane receptors involved in cell-cell and cell-extracellular matrix (ECM) interactions. Integrins are heterodimeric proteins formed by the association of alpha (α) and beta (β) subunits. In particular, ITGB2 pairs with various alpha integrin subunits to form key receptors known as beta-2 integrins. Beta-2 integrins are primarily expressed on leukocytes (white blood cells) and are essential for mediating cell adhesion, migration, phagocytosis, and immune surveillance. The four major integrins that involve ITGB2 are LFA-1 (αLβ2, CD11a/CD18), Mac-1 (αMβ2, CD11b/CD18), gp150/95 (αXβ2, CD11c/CD18), and αDβ2 (CD11d/CD18). These integrins are vital for the immune system's ability to respond to infections and regulate inflammation.
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