Mouse Integrin Alpha V (ITGaV) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein ITGAV
proveedor
Abbexareference
abx167270Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Integrin alpha-V Protein is a recombinant Mouse protein expressed in E. coli.
Background
Integrin subunit alpha V (ITGAV) is a crucial component of the integrin family, a group of transmembrane receptors involved in cell-cell and cell-extracellular matrix (ECM) interactions. Integrins are heterodimeric proteins composed of alpha (α) and beta (β) subunits that, when combined, form receptors with various functions, primarily in cell adhesion, migration, proliferation, and signal transduction. ITGAV plays a particularly important role in binding to multiple ligands, including vitronectin, fibronectin, osteopontin, and components of the ECM, enabling it to mediate diverse biological processes such as angiogenesis, tissue repair, immune responses, and tumorigenesis. The gene encoding integrin alpha V (ITGAV) is located on chromosome 2q31.1 in humans. ITGAV pairs with several beta subunits (particularly β1, β3, β5, β6, and β8) to form distinct integrin heterodimers, each with unique ligand specificity and biological function. The most well-characterized integrins involving ITGAV are αvβ3, αvβ5, αvβ6, and αvβ8, which play significant roles in processes like wound healing, angiogenesis, and tumor progression.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Integrin Alpha V (ITGaV)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 31.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro71-Asp322 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ITGAV
dry ice
No
availability
Shipped within 5-7 working days.
alias
CD51,MSK8,VNRA,VTNR,Integrin alpha-V,Vitronectin receptor,Vitronectin receptor subunit alpha
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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