Mouse Integrin Alpha 3 (ITGA3) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ITGA3
proveedor
Abbexareference
abx168692Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ITGa3 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Integrin subunit alpha 3 (ITGA3) is part of the integrin family, which are heterodimeric transmembrane receptors crucial for mediating interactions between cells and the extracellular matrix (ECM). Integrins are essential for cell adhesion, migration, and signal transduction, contributing to various biological processes such as tissue repair, immune response, and embryonic development. ITGA3 pairs with integrin beta 1 (ITGB1) to form the α3β1 integrin, which serves as a receptor for laminin, fibronectin, and other ECM components, playing a vital role in cell adhesion and migration. ITGA3 is encoded by the ITGA3 gene, located on chromosome 17q21.33. The expression of ITGA3 is widespread, particularly in tissues such as epithelial cells, endothelial cells, and neurons. The α3β1 integrin is involved in important physiological processes like embryogenesis, angiogenesis, and wound healing, as well as in tumor metastasis and invasion in pathological conditions. In cancer biology, ITGA3 is often associated with tumor progression and can influence cellular invasiveness.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Integrin Alpha 3 (ITGA3)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 26.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe33-Glu236 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ITGA3
dry ice
No
availability
Shipped within 5-7 working days.
alias
JEB7,VL3A,CD49C,FRP-2,GAPB3,ILNEB,MSK18,VCA-2,VLA3a,GAP-B3,Integrin alpha-3,CD49 antigen-like family member C,Galactoprotein B3,VLA-3 subunit alpha
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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