Mouse Integrin Alpha 3 (ITGA3) CLIA Kit

Este producto es parte de ITGA3 - integrin subunit alpha 3
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845€ (96 tests)

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935106861
info@markelab.com
name
Mouse Integrin Alpha 3 (ITGA3) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492597
tested applications
CLIA

Description

Mouse Integrin alpha 3 (ITGa3) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Integrin Alpha 3 (ITGA3)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.118 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
JEB7,VL3A,CD49C,FRP-2,GAPB3,ILNEB,MSK18,VCA-2,VLA3a,GAP-B3,Integrin alpha-3,CD49 antigen-like family member C,Galactoprotein B3,VLA-3 subunit alpha
Background
CLIA Kits ITGA3
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Integrin subunit alpha 3 (ITGA3) is part of the integrin family, which are heterodimeric transmembrane receptors crucial for mediating interactions between cells and the extracellular matrix (ECM). Integrins are essential for cell adhesion, migration, and signal transduction, contributing to various biological processes such as tissue repair, immune response, and embryonic development. ITGA3 pairs with integrin beta 1 (ITGB1) to form the α3β1 integrin, which serves as a receptor for laminin, fibronectin, and other ECM components, playing a vital role in cell adhesion and migration. ITGA3 is encoded by the ITGA3 gene, located on chromosome 17q21.33. The expression of ITGA3 is widespread, particularly in tissues such as epithelial cells, endothelial cells, and neurons. The α3β1 integrin is involved in important physiological processes like embryogenesis, angiogenesis, and wound healing, as well as in tumor metastasis and invasion in pathological conditions. In cancer biology, ITGA3 is often associated with tumor progression and can influence cellular invasiveness.

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