Mouse Integrin Alpha 1 (ITGa1) ELISA Kit
702€ (96 tests)
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name
Mouse Integrin Alpha 1 (ITGa1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx154221
tested applications
ELISA
Description
Mouse Integrin Alpha 1 (ITGa1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Integrin alpha 1 concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Integrin Alpha 1 (ITGa1)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Integrin Alpha 1 (ITGa1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 31 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | VLA-1,VLA1,CD49a,CD49 antigen-like family member A,Laminin and collagen receptor |
| Background | Elisa Kits for: ITGA1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Integrin subunit alpha 1 (ITGA1) is a member of the integrin family, a group of transmembrane receptors involved in cell-extracellular matrix (ECM) adhesion and cell-cell interactions. Integrins are heterodimeric molecules composed of an alpha and beta subunit that combine to form functional receptors. These receptors are critical for mediating cell adhesion, migration, proliferation, and signal transduction across the plasma membrane. ITGA1, specifically, pairs with integrin beta 1 (ITGB1) to form the α1β1 integrin, which primarily serves as a receptor for collagen and laminin in the extracellular matrix. The ITGA1 gene, located on chromosome 5q11.2, encodes the alpha 1 subunit, which is involved in binding to collagen types I and IV. This binding plays a significant role in the regulation of cellular responses such as matrix remodeling, wound healing, inflammation, and cell differentiation. ITGA1 expression is found across various tissues, including the kidney, liver, smooth muscle cells, fibroblasts, and immune cells, reflecting its diverse physiological functions. Additionally, ITGA1 has emerged as an important player in tumor biology, where it can influence cancer cell adhesion, invasion, and metastasis.
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