Mouse Hyaluronan Mediated Motility Receptor (HMMR) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Hyaluronan Mediated Motility Receptor (HMMR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx521174
tested applications
ELISA
Description
Mouse Hyaluronan Mediated Motility Receptor (HMMR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Hyaluronan Mediated Motility Receptor (HMMR) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Hyaluronan Mediated Motility Receptor (HMMR) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 15.6 pg/ml - 1000 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q00547 |
| Alias | CD168,IHABP,RHAMM,Intracellular hyaluronic acid-binding protein,Receptor for hyaluronan-mediated motility |
| Background | Elisa kits for HMMR |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
The hyaluronan-mediated motility receptor (HMMR), also known as RHAMM (Receptor for Hyaluronan-Mediated Motility), is a protein encoded by the HMMR gene in humans. Originally identified in studies focusing on cancer cell motility, HMMR functions as a receptor for hyaluronan (HA), a component of the extracellular matrix (ECM) involved in tissue hydration, structural integrity, and cellular communication. HMMR has attracted significant scientific interest due to its roles in cellular adhesion, proliferation, migration, and wound healing. Its expression is often upregulated in cancer cells, contributing to increased cell motility and invasiveness, making it a focal point in oncology research. HMMR functions not only as a surface receptor but also intracellularly, interacting with various signaling pathways and microtubule networks, which influences cell division and chromosomal stability. Given its involvement in pathways like RAS and ERK and its interaction with the mitotic spindle, HMMR is critical in cell cycle regulation and tissue morphogenesis. Dysregulated HMMR expression has been associated with cancer progression, inflammatory diseases, and even osteoarthritis, placing it at the intersection of various physiological and pathological processes.
Related Products
Human HMMR (Hyaluronan mediated motility receptor) ELISA Kit
Ver Producto
HMMR-Specific antibody
Ver ProductoHMMR antibody
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Ver Producto