Mouse Hepatocyte Nuclear Factor 4 Alpha (HNF4a) ELISA Kit
715€ (96 tests)
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Name
Mouse Hepatocyte Nuclear Factor 4 Alpha (HNF4a) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx254177
Tested Applications
ELISA
Description
Mouse Hepatocyte Nuclear Factor 4 Alpha (HNF4a) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Hepatocyte Nuclear Factor 4 Alpha concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Documentos del producto
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Hepatocyte Nuclear Factor 4 Alpha (HNF4a) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 39.1 pg/ml - 2500 pg/ml |
| Sensitivity | 23.4 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P49698 |
| Gene ID | 15378 |
| Alias | TCF,HNF4,MODY,FRTS4,MODY1,NR2A1,TCF14,HNF4a7,HNF4a8,HNF4a9,NR2A21,TCF-14,HNF4alpha,Transcription factor HNF-4,Nuclear receptor subfamily 2 group A member 1 |
| Background | Elisa Kits for: HNF4A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
Hepatocyte nuclear factor 4 alpha (HNF4A) is a critical transcription factor that plays a key role in regulating liver function, metabolism, and the development of the gastrointestinal tract HNF4A is highly expressed in the liver, where it controls the expression of genes involved in hepatic glucose production, lipid metabolism, and bile acid synthesis It also regulates the development and differentiation of liver cells and contributes to maintaining liver homeostasis HNF4A is involved in controlling genes responsible for the metabolism of steroids, carbohydrates, and lipids, and it is crucial for maintaining the liver's metabolic functions Dysregulation of HNF4A has been associated with metabolic diseases, such as diabetes, non-alcoholic fatty liver disease (NAFLD), and liver cirrhosis In addition, mutations in the HNF4A gene can lead to maturity-onset diabetes of the young (MODY), a form of diabetes characterized by early-onset, autosomal dominant inheritance of insulin resistance
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