Mouse Hepatitis B Virus X Interacting Protein (LAMTOR5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for LAMTOR5
proveedor
Abbexareference
abx516349Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Hepatitis B Virus X Interacting Protein (LAMTOR5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ragulator complex protein LAMTOR5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Ragulator complex protein LAMTOR5 is a critical subunit of the Ragulator complex that anchors Rag GTPases to the lysosomal membrane, facilitating the activation of mTORC1 in response to amino acid and nutrient availability LAMTOR5 stabilizes the Ragulator complex structure and supports mTORC1 signaling, which is essential for regulating cellular metabolism, growth, and autophagy Its role in nutrient sensing and lysosomal positioning makes it vital for cellular homeostasis Studies highlight that loss or dysregulation of LAMTOR5 disrupts mTORC1 activation, leading to impaired protein synthesis, autophagy, and energy balance LAMTOR5 is also involved in immune responses, where mTORC1 signaling regulates T-cell activation and macrophage function Aberrant expression of LAMTOR5 has been linked to metabolic disorders, neurodegenerative diseases, and cancers, where impaired nutrient signaling promotes cellular dysfunction Recent studies suggest its involvement in stress response pathways and lysosomal biogenesis, reinforcing its essential role as a scaffold protein in coordinating lysosome-mTORC1 communication
Características del producto
category
ELISA Kits
immunogen target
Hepatitis B Virus X Interacting Protein (LAMTOR5)
reactivity
Mouse
test range
1.56 ng/ml - 100 ng/ml
sensitivity
< 0.83 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
HBXIP,XIP,Hepatitis B virus X-interacting protein,Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LAMTOR5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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