Mouse Heparin Cofactor 2 (SERPIND1) ELISA Kit

Este producto es parte de SERPIND1 - serpin family D member 1
Mouse Heparin Cofactor 2 (SERPIND1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

585€ (96 tests)

Elisa kits for SERPIND1

proveedor

Abbexa

reference

abx254161

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Heparin Cofactor 2 (SERPIND1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Heparin Cofactor II concentrations in serum, plasma and other biological fluids.


Background

SERPIND1 encodes Heparin Cofactor II (HCII), a serine protease inhibitor (serpin) that plays a critical role in the regulation of coagulation. It shares functional similarities with antithrombin (SERPINC1), particularly in inhibiting thrombin, a key enzyme in the coagulation cascade. However, HCII exhibits a more specialized function as its activity is highly dependent on heparin-like glycosaminoglycans (GAGs), particularly dermatan sulfate, and to a lesser extent, heparin. HCII's involvement in thrombin inhibition and its activation through GAGs have made it an essential component in controlling clot formation and preventing thrombosis, particularly in vascular tissue. HCII deficiency has been linked to a predisposition for thromboembolic disorders and cardiovascular diseases.

Características del producto

category

ELISA Kits


immunogen target

Heparin Cofactor 2 (SERPIND1)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

HC2,LS2,HCF2,HCII,HLS2,THPH10,D22S673,Heparin cofactor 2,Heparin cofactor II,Protease inhibitor leuserpin-2,Serpin D1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

SERPIND1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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