Mouse Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
537.5€ (96 tests)
Elisa Kits GNRHR
proveedor
Abbexareference
abx576693Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Gonadotropin-releasing hormone receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
GNRHR is a G protein-coupled receptor (GPCR) expressed primarily in the anterior pituitary gland, where it binds gonadotropin-releasing hormone (GnRH). Upon activation, GNRHR stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which regulate gonadal function, steroidogenesis, and gametogenesis. GNRHR signaling occurs through Gq/11 proteins, activating phospholipase C (PLC), increasing intracellular calcium, and stimulating protein kinase C (PKC). It plays a central role in reproductive physiology, controlling the menstrual cycle in females and testosterone production in males. Mutations in GNRHR are linked to disorders such as hypogonadotropic hypogonadism, characterized by delayed puberty and infertility. GNRHR is also expressed in extra-pituitary tissues and certain cancers, such as breast, prostate, and ovarian cancers, where it regulates cell proliferation and survival. Therapeutically, GnRH agonists and antagonists are used to treat hormone-dependent conditions, including infertility, endometriosis, and cancers. GNRHR remains a critical target in reproductive medicine and oncology.
Características del producto
category
ELISA Kits
immunogen target
Gonadotropin Releasing Hormone Receptor (GNRHR)
reactivity
Mouse
test range
0.39 ng/ml - 25 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
GNRHR,luteinizing hormone-releasing hormone (LHRH) receptor,GNRHR1,LHRH receptor,Type I GnRHR,gnRH receptor,GnRH-R,GnRH I receptor,GnRHR,luliberin receptor ,LHRHR, GRHR, HH7, LHRHR,GnRH1 receptor
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
GNRHR
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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