Mouse Glycoprotein Ib Beta Polypeptide, Platelet (GP1Bb) CLIA Kit
845€ (96 tests)
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935106861
info@markelab.com
name
Mouse Glycoprotein Ib Beta Polypeptide, Platelet (GP1Bb) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492323
tested applications
CLIA
Description
Mouse GP1Bb Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Plasma.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Glycoprotein Ib Beta Polypeptide, Platelet (GP1Bb) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.25 pg/ml - 2000 pg/ml |
| Sensitivity | < 14.7 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Plasma. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | BS,CD42C,GPIBB,BDPLT1,GPIbbeta,Platelet glycoprotein Ib beta chain, GP-Ib beta,GPIb-beta,GPIbB,Antigen CD42b-beta,CD42c |
| Background | CLIA Kits GP1BB |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Glycoprotein Ib platelet subunit beta (GP1BB) is a critical component of the Glycoprotein Ib-IX-V (GPIb-IX-V) complex, a receptor complex expressed on the surface of platelets. This receptor is central to platelet adhesion under conditions of high shear stress and plays a pivotal role in the initiation of platelet plug formation, particularly in arterial circulation where rapid blood flow is present. The GPIb-IX-V complex interacts with von Willebrand factor (vWF) to mediate the tethering of platelets to the site of vascular injury, marking the beginning of the hemostatic process that leads to clot formation and wound healing. GP1BB is the beta subunit of the GPIb-IX-V complex, and it is necessary for proper assembly and function of the entire receptor complex. The GP1BB protein contributes to the stability of the receptor on the platelet surface and forms part of the binding interface with other components of the GPIb-IX-V complex, including GP1BA, GPIX, and GPV.
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