Mouse Glycophorin C (GYPC) Protein
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Description
Glycophorin C Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Glycophorin C (GYPC) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 42.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Ile95 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q78HU7 |
| Alias | Gerbich blood group,GE,GPC,GPD,GYPD,CD236,PAS-2,CD236R,Glycoconnectin,Glycophorin-D,Glycoprotein beta, |
| Background | Protein GYPC |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Glycophorin C (GYPC) is a membrane glycoprotein found primarily on the surface of red blood cells (RBCs). It is a member of the glycophorin family, which includes Glycophorin A (GYPA) and Glycophorin B (GYPB). GYPC plays a crucial role in maintaining the structural integrity of the RBC membrane and contributes to the MNS blood group system. The protein is encoded by the GYPC gene located on chromosome 2. Along with its homologs GYPA and GYPB, GYPC is involved in defining RBC membrane characteristics, including cell shape, flexibility, and interactions with the cytoskeleton. GYPC, specifically, is known to carry the M and N antigens of the MNS blood group system, which are significant in transfusion medicine. In addition to its structural function in the RBC membrane, GYPC plays a role in the function of the erythrocyte by interacting with various signaling molecules and maintaining the membrane's elasticity and resistance to mechanical stresses. Its functional importance in RBCs, as well as its potential relevance in certain disease states, makes it a significant protein in both clinical and biological research.
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