Mouse Glutamyl Aminopeptidase (ENPEP) CLIA Kit
845€ (96 tests)
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935106861
info@markelab.com
name
Mouse Glutamyl Aminopeptidase (ENPEP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492141
tested applications
CLIA
Description
Mouse Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Glutamyl Aminopeptidase (ENPEP) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.062 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | APA,CD249,gp160,EAP,Aminopeptidase A,AP-A,Differentiation antigen gp160 |
| Background | CLIA Kits ENPEP |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Glutamyl aminopeptidase (ENPEP), also known as aminopeptidase A (APA) or CD249, is a zinc-dependent metallopeptidase involved in the regulation of blood pressure, modulation of immune responses, and amino acid metabolism. ENPEP is encoded by the ENPEP gene and functions primarily by cleaving N-terminal glutamyl and aspartyl residues from peptide substrates. As a member of the M1 family of aminopeptidases, ENPEP is a single-pass membrane protein found predominantly in kidney, intestine, and endothelial tissues. It also exists in various immune cells and is a critical regulator in the renin-angiotensin system (RAS), where it facilitates the conversion of angiotensin II to angiotensin III, thereby influencing blood pressure and fluid balance. ENPEP’s role in the RAS system is pivotal because of its impact on hypertension, cardiovascular diseases, and kidney functions. Additionally, ENPEP has implications in immune response regulation, making it a potential target in the treatment of inflammatory and autoimmune diseases. Research into ENPEP function and expression patterns is essential to better understand how this enzyme could be modulated for therapeutic benefits in hypertension, metabolic disorders, and immune system-related diseases.
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