Mouse Follistatin Like Protein 1 (FSTL1) Protein

247€ (10 µg)
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935106861
info@markelab.com
name
Mouse Follistatin Like Protein 1 (FSTL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691348
tested applications
SDS-PAGE
Description
Mouse Follistatin-Like 1 Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Follistatin-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Glu19-Ile306 is expressed with a Fc tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Follistatin-Like 1 |
Host | Human |
Origin | Mouse |
Observed MW | Molecular Weight: 59.6 kDa Sequence Fragment: Glu19-Ile306 Tag: C-terminal Fc tag |
Expression | Recombinant |
Purity | > 95% (SDS-PAGE) |
Size 1 | 10 µg |
Size 2 | 50 µg |
Form | Lyophilized |
Tested Applications | SDS-PAGE |
Buffer | PBS, pH7.4. |
Availability | Shipped within 5-15 working days. |
Storage | Store at < -20°C. |
Dry Ice | No |
UniProt ID | Q62356 |
Alias | FRP,FSL1,OCC1,OCC-1,TSC36,MIR198,Follistatin-related protein 1 |
Background | Protein FSTL1 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Follistatin like 1 (FSTL1) FSTL1 is a secreted glycoprotein that belongs to the SPARC (Secreted Protein Acidic and Rich in Cysteine)-related family and plays diverse roles in development, inflammation, and tissue repair. FSTL1 contains a follistatin-like domain that enables it to interact with various signaling molecules, including members of the TGF-β superfamily. FSTL1 modulates signaling pathways such as BMP (bone morphogenetic protein) signaling, influencing cell differentiation, growth, and immune responses. It is highly expressed in tissues undergoing development or repair, such as the heart, lungs, and skeletal muscles. FSTL1 also exhibits immunomodulatory properties, acting as a pro-inflammatory or anti-inflammatory mediator depending on the context. Dysregulation of FSTL1 has been implicated in inflammatory diseases, cardiovascular conditions, and fibrosis, where it contributes to tissue remodeling and immune dysregulation. In cancer, altered FSTL1 expression can influence tumor progression and metastasis by modulating the tumor microenvironment. Its multifunctional roles in signaling, tissue repair, and immune regulation highlight its potential as a therapeutic target.
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