Mouse Follistatin Like Protein 1 (FSTL1) Protein

Este producto es parte de FSTL - Follistatin-like protein
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247€ (10 µg)

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935106861
info@markelab.com
name
Mouse Follistatin Like Protein 1 (FSTL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691348
tested applications
SDS-PAGE

Description

Mouse Follistatin-Like 1 Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Follistatin-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Glu19-Ile306 is expressed with a Fc tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Follistatin-Like 1
Host
Human
Origin
Mouse
Observed MW
Molecular Weight: 59.6 kDa
Sequence Fragment: Glu19-Ile306
Tag: C-terminal Fc tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
PBS, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
Q62356
Alias
FRP,FSL1,OCC1,OCC-1,TSC36,MIR198,Follistatin-related protein 1
Background
Protein FSTL1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Follistatin like 1 (FSTL1) FSTL1 is a secreted glycoprotein that belongs to the SPARC (Secreted Protein Acidic and Rich in Cysteine)-related family and plays diverse roles in development, inflammation, and tissue repair. FSTL1 contains a follistatin-like domain that enables it to interact with various signaling molecules, including members of the TGF-β superfamily. FSTL1 modulates signaling pathways such as BMP (bone morphogenetic protein) signaling, influencing cell differentiation, growth, and immune responses. It is highly expressed in tissues undergoing development or repair, such as the heart, lungs, and skeletal muscles. FSTL1 also exhibits immunomodulatory properties, acting as a pro-inflammatory or anti-inflammatory mediator depending on the context. Dysregulation of FSTL1 has been implicated in inflammatory diseases, cardiovascular conditions, and fibrosis, where it contributes to tissue remodeling and immune dysregulation. In cancer, altered FSTL1 expression can influence tumor progression and metastasis by modulating the tumor microenvironment. Its multifunctional roles in signaling, tissue repair, and immune regulation highlight its potential as a therapeutic target.

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