Mouse Fibroblast Growth Factor Receptor Like 1 (FGFRL1) ELISA Kit

Este producto es parte de FGFRL1 - fibroblast growth factor receptor like 1
Mouse Fibroblast Growth Factor Receptor Like 1 (FGFRL1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits FGFRL1

proveedor

Abbexa

reference

abx389293

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Fibroblast Growth Factor Receptor Like 1 (FGFRL1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse FGFRL1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Fibroblast growth factor receptor like 1 (FGFRL1) FGFRL1 is a unique member of the FGFR family that lacks the intracellular tyrosine kinase domain, distinguishing it from other FGFRs. FGFRL1 contains an extracellular ligand-binding domain similar to other FGFRs, capable of binding FGFs and interacting with heparan sulfate proteoglycans. However, instead of activating intracellular signaling cascades, FGFRL1 is thought to act as a decoy receptor, modulating FGF availability and signaling. FGFRL1 plays a role in skeletal development, cartilage formation, and kidney morphogenesis, as evidenced by its high expression in these tissues during development. Mutations or dysregulation of FGFRL1 have been linked to skeletal abnormalities, including craniosynostosis and cartilage defects. Additionally, FGFRL1 may influence cellular adhesion and migration through interactions with extracellular matrix components. Its distinctive lack of kinase activity highlights its role as a regulatory rather than a signaling receptor in FGF-mediated processes.

Características del producto

category

ELISA Kits


immunogen target

Fibroblast Growth Factor Receptor Like 1 (FGFRL1)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

FHFR,FGFR5,FGFR-5,Fibroblast growth factor receptor 5,FGFR-like protein,FGF homologous factor receptor,FGF receptor-like protein 1


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

FGFRL1


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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