Mouse Estrogen Receptor Beta (ESR2) ELISA Kit
643.5€ (96 tests)
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Name
Mouse Estrogen Receptor Beta (ESR2) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx153966
Tested Applications
ELISA
Description
Mouse Estrogen Receptor Beta (ESR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Estrogen Receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Estrogen Receptor 2
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Estrogen Receptor Beta (ESR2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.15 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O08537 |
| Gene ID | 13983 |
| Alias | Erb,ESRB,ODG8,ESTRB,NR3A2,ER-BETA,ESR-BETA,Estrogen receptor beta,Nuclear receptor subfamily 3 group A member 2 |
| Background | Elisa Kits for: ESR2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
Estrogen receptor 2 (ESR2), also known as ERβ, is a closely related nuclear receptor that also mediates the effects of estrogen but has distinct roles compared to ESR1 ESR2 is expressed in a wide range of tissues, including the ovaries, prostate, brain, and cardiovascular system, where it regulates gene expression related to reproductive health, neuroprotection, and cardiovascular function ESR2 has a unique role in modulating the balance of estrogenic signaling, often acting to counterbalance the effects of ESR1 in certain tissues, such as the breast and prostate In the brain, ESR2 plays a protective role in neuronal function and is involved in processes like cognition, neurogenesis, and synaptic plasticity In addition to its neuroprotective functions, ESR2 is important for cardiovascular health, where it helps regulate vascular tone and reduce inflammation Dysregulation of ESR2 signaling is implicated in conditions such as cardiovascular disease, prostate cancer, and neurodegenerative diseases Its distinct functions make ESR2 an important target for therapeutic strategies aimed at treating estrogen-related diseases, with potential benefits in managing conditions like cancer, neurodegeneration, and cardiovascular disorders
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