Mouse Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) ELISA Kit

Este producto es parte de DDR1 - discoidin domain receptor tyrosine kinase 1
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559€ (96 tests)

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935106861
info@markelab.com
name
Mouse Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx570635
tested applications
ELISA

Description

Mouse Epithelial discoidin domain-containing receptor 1 ELISA Kit is an ELISA kit against Mouse Epithelial discoidin domain-containing receptor 1 (Ddr1).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q03146
Alias
Epithelial discoidin domain-containing receptor 1,Epithelial discoidin domain receptor 1,CA, DDR,NEP,HGK2,PTK3,RTK6,TRKE,CD167,EDDR1,MCK10,NTRK4,PTK3A,Discoidin receptor tyrosine kinase,Mammary carcinoma kinase 10
Background
Elisa kits for DDR1
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase (RTK) that uniquely binds to collagens, distinguishing it from other RTKs that are primarily activated by growth factors or hormones. DDR1 is encoded by the DDR1 gene located on chromosome 6p21.3 in humans and is widely expressed across various tissues, including the kidneys, brain, lungs, and reproductive organs. DDR1 has critical roles in cell adhesion, proliferation, migration, and differentiation, primarily through its unique capacity to interact with the extracellular matrix (ECM), particularly collagens. As a collagen-binding receptor, DDR1 is involved in cellular responses to structural changes in the ECM, making it essential in tissue remodeling, wound healing, and organ development. DDR1 has become increasingly significant in the context of cancer biology due to its involvement in cell adhesion and motility, which are critical for metastasis. It is also implicated in fibrotic diseases, where it contributes to tissue stiffness and fibrosis, and in immune response modulation. The discovery of DDR1 has broadened the understanding of RTKs, as it revealed a subset of kinases that function primarily through interactions with ECM proteins, underscoring its role in both physiological and pathological conditions.

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