Mouse Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 3 (ENPP3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 3 (ENPP3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx522060
tested applications
ELISA
Description
Mouse Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 3 (ENPP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 3 (ENPP3) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 3 (ENPP3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6DYE8 |
| Alias | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3,Alkaline phosphodiesterase I,B10,NPP3,PDNP3,CD203c,PD-IBETA,Phosphodiesterase I beta |
| Background | Elisa kits for ENPP3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ENPP3, or ectonucleotide pyrophosphatase/phosphodiesterase 3, is a member of the ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) family, which is involved in the hydrolysis of extracellular nucleotides and plays significant roles in cell signaling and metabolism. ENPP3, encoded by the ENPP3 gene in humans, is prominently expressed on the surface of various cell types, including epithelial cells, immune cells, and especially on mast cells and basophils. The enzyme's primary function is to hydrolyze extracellular nucleotide phosphates, such as ATP, ADP, and NAD+, producing pyrophosphate and nucleoside monophosphates as end products. These hydrolytic activities of ENPP3 influence signaling pathways that regulate inflammation, immune responses, and cellular proliferation. The activity of ENPP3 is particularly important in the modulation of immune responses and inflammation. By controlling extracellular nucleotide levels, ENPP3 indirectly regulates purinergic signaling, which is central to processes such as cell migration, cytokine release, and response to injury. ENPP3 dysregulation is associated with a range of pathological conditions, including allergic responses, autoimmune diseases, and some cancers, making it a potential therapeutic target for intervention in these diseases.
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