Mouse Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Protein

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Description
Mouse Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Protein is a Recombinant Mouse protein expressed in E. coli.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 37.3 kDa Observed MW: 37 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg16-Arg300 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 97% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized Reconstitute in ddH2O to a concentration between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Background | Protein DYRK1A |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody
DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.
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Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody
DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.
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