Mouse Dipeptidyl Peptidase 4 / CD26 (DPP4) Protein

Este producto es parte de DPP4 - dipeptidyl peptidase 4
Mouse Dipeptidyl Peptidase 4 / CD26 (DPP4) Protein

Pida mas información

935106861

info@markelab.com

Precio

2249€ (1 mg)

Protein DPP4

proveedor

Abbexa

reference

abx066346

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Dipeptidyl Peptidase IV (DPP4) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Dipeptidyl peptidase 4 (DPP4), also known as CD26, is a transmembrane glycoprotein and serine protease that plays a significant role in regulating glucose metabolism, immune function, and cell signaling. It is expressed on the surface of various cell types, including epithelial cells, endothelial cells, and immune cells such as T cells and B cells. DPP4 is widely known for its role in glucose homeostasis through its enzymatic activity, where it deactivates incretin hormones like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones promote insulin release in response to meals, and their inactivation by DPP4 reduces insulin secretion, thereby impacting blood sugar levels. Beyond its metabolic functions, DPP4 also participates in various immune regulatory pathways. As CD26, it is involved in T-cell activation and co-stimulation. DPP4 is linked to inflammatory processes and certain cancers, particularly due to its enzymatic activity and role in regulating immune responses. Additionally, the soluble form of DPP4 (sDPP4), which circulates in the plasma, plays a role in systemic metabolic and immune regulation.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Dipeptidyl Peptidase 4 / CD26 (DPP4)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

1 mg


size 2

5 mg


observerd MW

Molecular Weight: Calculated MW: 16.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser631-His760 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

DPP4


dry ice

No


availability

Shipped within 1-2 months.


alias

CD26,ADABP,ADCP2,DPPIV,TP103,Dipeptidyl peptidase 4,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,T-cell activation antigen CD26


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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