Mouse DENN domain-containing protein 1A (DENND1A) ELISA Kit

Este producto es parte de DENND - DENN domain containing
Mouse DENN domain-containing protein 1A (DENND1A) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DENND1A

proveedor

Abbexa

reference

abx510089

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse DENN domain-containing protein 1A (DENND1A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DENN domain-containing protein 1A concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DENN domain containing 1A (DENND1A) is a critical guanine nucleotide exchange factor (GEF) for Rab35, a small GTPase involved in endosomal trafficking and membrane recycling. DENND1A regulates the cycling of Rab35 between its GDP-bound inactive form and GTP-bound active state, promoting endosomal sorting and exocytosis. It is particularly important in processes like cytokinesis, where Rab35 facilitates the trafficking of vesicles required for the separation of daughter cells. DENND1A is also implicated in recycling plasma membrane components, such as receptors and transporters, ensuring proper cellular signaling and nutrient uptake. Dysregulation of DENND1A has been linked to pathological conditions, including polycystic ovary syndrome (PCOS), where it may contribute to hormonal imbalances and altered cellular signaling. Its tissue-specific expression, particularly in reproductive and endocrine tissues, underscores its specialized roles in vesicle trafficking and cellular function.

Características del producto

category

ELISA Kits


immunogen target

DENN domain-containing protein 1A (DENND1A)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

FAM31A,KIAA1608,Connecdenn 1,Connecdenn


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DENND1A


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

anti- DENND1A antibody

anti- DENND1A antibody

proveedor

FineTest

reference

FNab02332

Tested Applications

ELISA, WB, IF

reactivity

human

status

RUO

clonality

polyclonal

Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the ...

Precio a consultar

Ver más

DENN Domain Containing Protein 1A (DENND1A) Antibody

DENN Domain Containing Protein 1A (DENND1A) Antibody

proveedor

Abbexa

reference

abx232332

Tested Applications

ELISA, WB, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

DENND1A Antibody is a Rabbit Polyclonal against DENND1A.

364€ (100 µg)

Ver más

DENN Domain Containing Protein 1A (DENND1A) Antibody

DENN Domain Containing Protein 1A (DENND1A) Antibody

proveedor

Abbexa

reference

abx301528

Tested Applications

ELISA, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

DENND1A Antibody is a Rabbit Polyclonal against DENND1A.

169€ (20 µg)

Ver más