Mouse Dedicator of cytokinesis protein 8 (DOCK8) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DOCK8
proveedor
Abbexareference
abx510802Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Dedicator of cytokinesis protein 8 (DOCK8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 8 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
DOCK8 is a GEF primarily activating Rac1 and Cdc42, critical for actin cytoskeleton regulation, immune cell migration, and synapse formation. It is essential for lymphocyte survival, intercellular adhesion, and immune synapse organization. DOCK8 deficiency causes DOCK8 immunodeficiency syndrome, characterized by recurrent infections, allergies, and autoimmunity. It interacts with proteins like WASP and ELMO to promote immune cell migration and T-cell activation. DOCK8 is highly expressed in hematopoietic cells, particularly T and B cells. Dysregulation impairs lymphocyte trafficking and survival, contributing to immune dysfunction. Studies in knockout models show defects in T-cell proliferation, migration, and immune surveillance.
Características del producto
category
ELISA Kits
immunogen target
Dedicator of cytokinesis protein 8 (DOCK8)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
HEL-205,HIES2,MRD2,ZIR8
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DOCK8
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
anti- DOCK8 antibody

proveedor
FineTestreference
FNab02498Tested Applications
ELISA, WB, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalPotential guanine nucleotide exchange factor(GEF). GEF proteins activate some small GTPases by exchanging bound GDP for ...
Precio a consultar
Ver másDocking Protein 8 (DOCK8) Antibody

proveedor
Abbexareference
abx112013Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDedicator Of Cytokinesis 8 Antibody is a Rabbit Polyclonal antibody against Dedicator Of Cytokinesis 8.
637€ (100 µl)
Ver másDocking Protein 8 (DOCK8) Antibody

proveedor
Abbexareference
abx232498Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDOCK8 Antibody is a Rabbit Polyclonal against DOCK8.
364€ (100 µg)
Ver más