Mouse Dedicator of cytokinesis protein 7 (DOCK7) ELISA Kit

Este producto es parte de DOCK - Dedicator of Cytokinesis
Mouse Dedicator of cytokinesis protein 7 (DOCK7) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOCK7

proveedor

Abbexa

reference

abx510800

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Dedicator of cytokinesis protein 7 (DOCK7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 7 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DOCK7 is a GEF for Rac1 and Cdc42, playing a key role in axon formation, neuronal polarization, and Schwann cell myelination. It regulates actin cytoskeleton dynamics and microtubule stabilization in neurons. DOCK7 interacts with the WAVE complex to promote Rac1-mediated actin remodeling, essential for neuronal growth and cortical development. It also regulates cell cycle progression in neural progenitors and is involved in epithelial-to-mesenchymal transition (EMT) in cancer. DOCK7 dysregulation is linked to neurological disorders and tumor progression. Mouse models with DOCK7 loss exhibit defects in neural development, including axonal growth and Schwann cell function.

Características del producto

category

ELISA Kits


immunogen target

Dedicator of cytokinesis protein 7 (DOCK7)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DEE23, EIEE23, ZIR2,KIAA1771


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOCK7


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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