Mouse Dedicator of cytokinesis protein 7 (DOCK7) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DOCK7
proveedor
Abbexareference
abx510800Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Dedicator of cytokinesis protein 7 (DOCK7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
DOCK7 is a GEF for Rac1 and Cdc42, playing a key role in axon formation, neuronal polarization, and Schwann cell myelination. It regulates actin cytoskeleton dynamics and microtubule stabilization in neurons. DOCK7 interacts with the WAVE complex to promote Rac1-mediated actin remodeling, essential for neuronal growth and cortical development. It also regulates cell cycle progression in neural progenitors and is involved in epithelial-to-mesenchymal transition (EMT) in cancer. DOCK7 dysregulation is linked to neurological disorders and tumor progression. Mouse models with DOCK7 loss exhibit defects in neural development, including axonal growth and Schwann cell function.
Características del producto
category
ELISA Kits
immunogen target
Dedicator of cytokinesis protein 7 (DOCK7)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
DEE23, EIEE23, ZIR2,KIAA1771
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DOCK7
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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