Mouse Cytosolic Non-Specific Dipeptidase (CNDP2) Protein
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Description
Cytosolic Non-Specific Dipeptidase (CNDP2) protein is a recombinant protein expressed in HEK293 cells.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cytosolic Non-Specific Dipeptidase (CNDP2) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Asn475 Tag: C-terminal 6 His tag |
| Origin | Mouse |
| Observed MW | Calculated MW: 53.8 kDa Observed MW (SDS-PAGE): 56-60 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | 0.2 µm filtered. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris-HCl, 150 mM NaCl, pH 8.0, containing 10% Glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. Shelf Life: 6 months. |
| Dry Ice | No |
| Background | Protein CNDP2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
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Human CNDP2 (Cytosolic non-specific dipeptidase) ELISA Kit
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CNDP2 antibody
Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343).
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