Mouse Complement C4 (C4) Protein

Este producto es parte de Complement C4A (Chido/Rodgers blood group)
Mouse Complement C4 (C4) Protein
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Mouse Complement C4 (C4) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx167319
Tested Applications
WB, SDS-PAGE

Description

Mouse Complement C4 (C4) Protein is a recombinant Mouse protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Complement C4 (C4)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Pro1450-Gln1723
Tag: N-terminal His tag
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Calculated MW: 34.8 kDa  Observed MW (SDS-PAGE): 35 kDa
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P01029
Alias
C4,RG,C4S,CO4,C4A2,C4A3,C4A4,C4A6,C4AD,CPAMD2,Acidic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
Background
Protein C4A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 350 µg/ml

Background

Complement C4A (Chido/Rodgers blood group) is a component of the classical complement pathway, which plays a crucial role in immune defense and inflammation C4A is involved in the formation of the C3 convertase complex, which leads to the activation of the complement cascade, promoting opsonization, pathogen destruction, and inflammation The Chido and Rodgers antigens are variants of C4A that are of clinical interest due to their association with blood transfusion reactions and their use as markers in blood group systems Complement C4A, along with C4B, contributes to the body's ability to fight infections, clear immune complexes, and resolve inflammation Dysregulation of C4A has been implicated in autoimmune diseases, such as lupus, where complement activation exacerbates tissue damage and inflammation C4A also influences immune responses to cancer, where its role in immune complex clearance can impact tumor progression and metastasis Understanding C4A and its polymorphisms is crucial for improving clinical approaches to immune modulation and blood group testing

Productos relacionados

abx019061

Complement Component C4 Beta Chain (C4-beta) Antibody

Complement C4 beta chain Antibody is a Rabbit Polyclonal antibody against Human.…

Ver producto
abx023306

Complement C4 (C4) Antibody

Complement C4 Antibody is a Goat polyclonal antibody for proteins and bioactive peptides against Complement C4.…

Ver producto
abx023307

Complement C4 (C4) Antibody

Complement C4 Antibody is a Goat polyclonal antibody for proteins and bioactive peptides against Complement C4.…

Ver producto