Mouse Complement C4-B (C4B) Protein

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935106861
info@markelab.com
Precio
1872€ (1 mg)
Protein C4B
proveedor
Abbexareference
abx653016Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse Complement C4-B (C4B) Protein is a Recombinant Mouse protein expressed in E. coli.
Background
C4B is a component of the classical and lectin pathways of the complement system, which plays an essential role in immune defense by promoting pathogen clearance, inflammation, and immune complex removal C4B is involved in the formation of the C3 convertase complex, which activates the complement cascade and results in the destruction of pathogens via opsonization and lysis It also participates in the regulation of immune responses and plays a role in clearing immune complexes that could otherwise contribute to tissue damage C4B is implicated in the Chido/Rodgers blood group system, which is used in transfusion medicine C4B deficiency or dysfunction is associated with autoimmune diseases, including systemic lupus erythematosus, where excessive complement activation exacerbates tissue damage The balance of C4B in the complement system is crucial for maintaining immune homeostasis and preventing chronic inflammation
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Complement C4-B (C4B)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
1 mg
size 2
5 mg
observerd MW
Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
C4B
dry ice
No
availability
Shipped within 1-2 months.
alias
CH,C4F,CO4,C4B1,C4B2,C4B3,C4B5,C4BD,C4B12,C4B_2,CPAMD3,Basic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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