Mouse Complement Fragment C4a (C4a) ELISA Kit
![Mouse Complement Fragment C4a (C4a) ELISA Kit](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fcatalog%2FGraphs%2F971%2Fabx255224%2Fabx255224_Mouse_Complement_Component_4a_C4A_ELISA_Kit_graph-250x250.png&w=3840&q=75)
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935106861
info@markelab.com
Precio
525€ (96 tests)
Elisa Kits C4
proveedor
Abbexareference
abx255224Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Complement Fragment C4a (C4a) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Complement Fragment C4a (C4a) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
Complement C4A (Chido/Rodgers blood group) is a component of the classical complement pathway, which plays a crucial role in immune defense and inflammation C4A is involved in the formation of the C3 convertase complex, which leads to the activation of the complement cascade, promoting opsonization, pathogen destruction, and inflammation The Chido and Rodgers antigens are variants of C4A that are of clinical interest due to their association with blood transfusion reactions and their use as markers in blood group systems Complement C4A, along with C4B, contributes to the body's ability to fight infections, clear immune complexes, and resolve inflammation Dysregulation of C4A has been implicated in autoimmune diseases, such as lupus, where complement activation exacerbates tissue damage and inflammation C4A also influences immune responses to cancer, where its role in immune complex clearance can impact tumor progression and metastasis Understanding C4A and its polymorphisms is crucial for improving clinical approaches to immune modulation and blood group testing
Características del producto
category
ELISA Kits
immunogen target
Complement Fragment C4a (C4a)
reactivity
Mouse
test range
78 pg/ml - 5000 pg/ml
sensitivity
46.9 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
C4,RG,C4S,CO4,C4A2,C4A3,C4A4,C4A6,C4AD,CPAMD2,Acidic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
C4A
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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