Mouse Cluster of Differentiation 99 (CD99) Protein

Este producto es parte de CD99 - CD99 molecule
Mouse Cluster of Differentiation 99 (CD99) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein CD99

proveedor

Abbexa

reference

abx168703

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse CD99 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

CD99, also known as MIC2, is a cell surface glycoprotein expressed on various cell types, including leukocytes, endothelial cells, and certain tumor cells. The CD99 protein plays a role in multiple biological processes, such as cell adhesion, migration, apoptosis, and immune regulation. CD99 expression is crucial in thymocyte differentiation and T cell activation, as well as in leukocyte extravasation, where immune cells move from blood vessels to sites of inflammation. It is also involved in neural cell adhesion and spermatogenesis, highlighting its diverse functional roles across cell types and tissues. CD99 has garnered attention for its clinical implications, especially in cancer, as it is overexpressed in Ewing sarcoma and other tumors, making it a biomarker of diagnostic and therapeutic interest. Additionally, CD99 is involved in the immune response, where it contributes to the regulation of leukocyte activity and inflammation. The molecule also plays a role in apoptosis, promoting cell death in specific contexts, and has a dual role in tumor biology, both enhancing and inhibiting tumor progression depending on the cancer type and tissue context.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Cluster of Differentiation 99 (CD99)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 16.5 kDa Observed MW (SDS-PAGE): 19 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala27-Gln161 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD99


dry ice

No


availability

Shipped within 5-7 working days.


alias

Xg blood group,MIC2,HBA71,MIC2X,MIC2Y,MSK5X,Protein MIC2,T-cell surface glycoprotein E2


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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