Mouse Cluster of Differentiation 226 (CD226) Protein
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935106861
info@markelab.com
Precio
562.5€ (50 µg)
Protein CD226
proveedor
Abbexareference
abx692737Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse CD226 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse DNAM1 (NP_848802.2) extracellular domain (Met 1-Pro 254) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Background
CD226, also known as DNAX Accessory Molecule-1 (DNAM-1), is a critical glycoprotein that plays a significant role in the immune system. It is encoded by the CD226 gene located on chromosome 18q22.3. This molecule is predominantly expressed on the surface of various immune cells, including natural killer (NK) cells, T cells, monocytes, and platelets. The expression of CD226 is crucial for the regulation and activation of immune responses against tumors and infections. CD226 was initially identified due to its involvement in the adhesion and activation of NK cells and T cells. Its significance has expanded to various immunological processes, including cytotoxicity, cytokine production, and immune cell signaling. The interaction of CD226 with its ligands, such as CD155 (PVR) and CD112 (Nectin-2), is vital for the mediation of immune responses.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
HEK293 cells
immunogen target
CD226
host
HEK293 cells
tested applications
SDS-PAGE
size 1
50 µg
size 2
100 µg
expression
Recombinant
purity
> 97% (SDS-PAGE)
buffer
Lyophilized from sterile PBS, pH 7.4.
storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
or code
CD226
dry ice
No
availability
Shipped within 5-15 working days.
alias
PTA1,DNAM1,DNAM-1,TLiSA1,DNAX accessory molecule 1
NCBI accession
NP_848802.2
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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