Mouse Cluster of Differentiation 226 (CD226) Protein

Este producto es parte de CD226 molecule
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247€ (10 µg)

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935106861
info@markelab.com
name
Mouse Cluster of Differentiation 226 (CD226) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690089
tested applications
SDS-PAGE

Description

Mouse DNAX Accessory Molecule-1 Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse DNAX Accessory Molecule-1 is produced by our Mammalian expression system and the target gene encoding Glu19-Pro254 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
DNAX Accessory Molecule-1
Host
Human
Origin
Mouse
Observed MW
Molecular Weight: 27.6 kDa
Sequence Fragment: Met1-Pro254
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
PBS, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
NCBI Accession
NP_848802.2
Alias
PTA1,DNAM1,DNAM-1,TLiSA1,DNAX accessory molecule 1
Background
Protein CD226
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD226, also known as DNAX Accessory Molecule-1 (DNAM-1), is a critical glycoprotein that plays a significant role in the immune system. It is encoded by the CD226 gene located on chromosome 18q22.3. This molecule is predominantly expressed on the surface of various immune cells, including natural killer (NK) cells, T cells, monocytes, and platelets. The expression of CD226 is crucial for the regulation and activation of immune responses against tumors and infections. CD226 was initially identified due to its involvement in the adhesion and activation of NK cells and T cells. Its significance has expanded to various immunological processes, including cytotoxicity, cytokine production, and immune cell signaling. The interaction of CD226 with its ligands, such as CD155 (PVR) and CD112 (Nectin-2), is vital for the mediation of immune responses.

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