Mouse Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes (CDON) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes (CDON) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx388827
tested applications
ELISA
Description
Mouse Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes (CDON) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse CDON concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes (CDON) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q32MD9 |
| Gene ID | 57810 |
| Alias | CDO,Ihog,CDON1,HPE11,ORCAM |
| Background | Elisa kits for CDON |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CDON (Cell adhesion molecule-related/downregulated by oncogenes) is a member of the immunoglobulin superfamily that functions as a co-receptor for the Hedgehog (Hh) signaling pathway, playing a critical role in embryonic development, cell differentiation, and tissue patterning. CDON is widely expressed in developing tissues and mediates cell-cell interactions necessary for proper neural, muscular, and skeletal development. It interacts with Hedgehog ligands and other cell adhesion molecules to facilitate signaling and influence cellular proliferation and migration. Mutations or loss of CDON function have been linked to developmental defects such as holoprosencephaly, a condition characterized by incomplete brain and craniofacial development. CDON has also been implicated in cancer, where its dysregulation can either promote or inhibit tumor progression depending on the context. It contains extracellular Ig-like domains and fibronectin type III repeats essential for ligand binding and signaling, as well as intracellular domains that engage cytoplasmic effectors. Research suggests that CDON acts as a tumor suppressor in certain cancers, making it a potential therapeutic target in oncology.
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