Mouse Caspase recruitment domain-containing protein 11 (CARD11) ELISA Kit

Este producto es parte de CARD - Caspase recruitment domain-containing protein
Mouse Caspase recruitment domain-containing protein 11 (CARD11) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for CARD11

proveedor

Abbexa

reference

abx504785

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Caspase recruitment domain-containing protein 11 (CARD11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Caspase recruitment domain-containing protein 11 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

CARD11, also known as CARMA1 (Caspase Recruitment Domain-Containing Membrane-Associated Protein 1), is a critical protein in the immune system, particularly in T-cell receptor (TCR) and B-cell receptor (BCR) signaling. It acts as an adaptor protein, linking upstream receptor activation to downstream signaling pathways, including the NF-κB pathway. NF-κB activation plays an essential role in the immune response, cell survival, and inflammation. CARD11 is crucial in immune cell activation, differentiation, and the production of pro-inflammatory cytokines. Mutations or dysregulation of CARD11 can result in immune system disorders, including lymphomas, and are implicated in autoimmune diseases such as systemic lupus erythematosus (SLE). Studies of CARD11's role in immune cell signaling have made it a potential therapeutic target for regulating immune responses and treating inflammatory or autoimmune diseases.

Características del producto

category

ELISA Kits


immunogen target

Caspase recruitment domain-containing protein 11 (CARD11)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CARD-containing MAGUK protein 1,CARMA1,BENTA, BIMP3, CARMA1, IMD11, IMD11A, PPBL


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

CARD11


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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