Mouse Caspase recruitment domain-containing protein 11 (CARD11) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CARD11
proveedor
Abbexareference
abx504785Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Caspase recruitment domain-containing protein 11 (CARD11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Caspase recruitment domain-containing protein 11 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CARD11, also known as CARMA1 (Caspase Recruitment Domain-Containing Membrane-Associated Protein 1), is a critical protein in the immune system, particularly in T-cell receptor (TCR) and B-cell receptor (BCR) signaling. It acts as an adaptor protein, linking upstream receptor activation to downstream signaling pathways, including the NF-κB pathway. NF-κB activation plays an essential role in the immune response, cell survival, and inflammation. CARD11 is crucial in immune cell activation, differentiation, and the production of pro-inflammatory cytokines. Mutations or dysregulation of CARD11 can result in immune system disorders, including lymphomas, and are implicated in autoimmune diseases such as systemic lupus erythematosus (SLE). Studies of CARD11's role in immune cell signaling have made it a potential therapeutic target for regulating immune responses and treating inflammatory or autoimmune diseases.
Características del producto
category
ELISA Kits
immunogen target
Caspase recruitment domain-containing protein 11 (CARD11)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CARD-containing MAGUK protein 1,CARMA1,BENTA, BIMP3, CARMA1, IMD11, IMD11A, PPBL
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CARD11
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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