Mouse Cadherin 5 (CDH5) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein CDH5
proveedor
Abbexareference
abx065627Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Cadherin 5 (CDH5) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Cadherin-5 (CDH5), also known as VE-cadherin (vascular endothelial cadherin), is a calcium-dependent adhesion protein primarily found in endothelial cells, which line blood and lymphatic vessels. It plays a critical role in maintaining the integrity and permeability of blood vessels by facilitating cell-cell adhesion between endothelial cells. CDH5 is essential for normal vascular development, and disruptions in its expression or function have been linked to various diseases, including cancer, cardiovascular diseases, and inflammatory conditions. As a classical cadherin, CDH5 belongs to a larger family of transmembrane proteins characterized by their cadherin repeats, which enable homophilic (same-type cell) binding and the formation of stable adherens junctions.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Cadherin 5 (CDH5)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 24.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp251-Ile426 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CDH5
dry ice
No
availability
Shipped within 5-7 working days.
alias
Cadherin-5,7B4,CD144,7B4 antigen,Vascular endothelial cadherin,VE-cadherin
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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