Mouse Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503780
tested applications
ELISA
Description
Mouse Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Brefeldin A-inhibited guanine nucleotide-exchange protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | A2A5R2 |
| Gene ID | 99371 |
| Alias | BIG2,PVNH2,Brefeldin A-inhibited GEP 2,Brefeldin A-inhibited guanine nucleotide-exchange protein 2 |
| Background | Elisa kits for ARFGEF2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2) is a guanine nucleotide exchange factor (GEF) that activates ADP-ribosylation factor (ARF) proteins, playing a key role in regulating cellular processes such as vesicular trafficking, actin cytoskeleton remodeling, and signal transduction ARFGEF2 promotes the exchange of GDP for GTP on ARF proteins, thus facilitating their activation and enabling the regulation of processes like vesicle formation, endocytosis, and the organization of cell membranes ARFGEF2 also regulates actin dynamics, contributing to cell migration, morphology, and division It plays a significant role in the immune system, where it influences immune cell trafficking and activation Dysregulation of ARFGEF2 has been associated with diseases such as cancer, where abnormal ARF and actin dynamics contribute to tumor cell migration and metastasis Additionally, ARFGEF2 is involved in the regulation of metabolic processes, and its dysfunction can lead to metabolic disorders, immune diseases, and cancer
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