Mouse Beta-1,4-Galactosyltransferase 7 (B4GALT7) ELISA Kit

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935106861

info@markelab.com

Precio

687.5€ (96 tests)

proveedor

Abbexa

reference

abx258000

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse B4GALT7 ELISA Kit is an ELISA Kit against B4GALT7.

Background

SAA proteins, belong to a family of apolipoproteins found in association with high-density lipoprotein (HDL) in plasma. These SAA proteins, consisting of 104 amino acids, are encoded within a closely-related gene family and have remained remarkably conserved throughout the course of vertebrate evolution. Notably, fragments of SAA at their amino-terminal end can aggregate into highly structured, insoluble fibrils that accumulate in what is referred to as "secondary" amyloid diseases. In mice, three acute-phase SAA isoforms have been identified, (SAA1, SAA2, and SAA3). During episodes of inflammation, SAA1 and SAA2 are primarily expressed and induced in the liver, whereas SAA3 sees induction in various distinct tissues. In contrast, humans possess a fourth SAA, known as SAA4, which is constitutively expressed in the liver and is thus categorized as constitutive SAA (C-SAA). It's worth noting that a similar protein, now also referred to as SAA4, has been identified in mice


Las proteínas SAA pertenecen a una familia de apolipoproteínas que se encuentran asociadas con las lipoproteínas de alta densidad (HDL) en el plasma. Estas proteínas SAA, que constan de 104 aminoácidos, están codificadas dentro de una familia de genes estrechamente relacionada y se han conservado notablemente a lo largo de la evolución de los vertebrados. En particular, los fragmentos de SAA en su extremo amino terminal pueden agregarse en fibrillas insolubles altamente estructuradas que se acumulan en lo que se conoce como enfermedades amiloides "secundarias". En ratones, se han identificado tres isoformas de SAA de fase aguda (SAA1, SAA2 y SAA3). Durante los episodios de inflamación, SAA1 y SAA2 se expresan e inducen principalmente en el hígado, mientras que SAA3 se induce en varios tejidos distintos. Por el contrario, los seres humanos poseen un cuarto SAA, conocido como SAA4, que se expresa constitutivamente en el hígado y, por tanto, se clasifica como SAA constitutivo (C-SAA). Vale la pena señalar que se ha identificado en ratones una proteína similar, ahora también conocida como SAA4.

Características del producto

immunogen target

Beta-1,4-Galactosyltransferase 7 (B4GALT7)


category

ELISA Kits


size 1

96 tests


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


uniprot id

Q9UBV7


gene id

11285


OMIM

130070


test range

78.12 pg/ml - 5000 pg/ml


sensitiviy

< 46.9 pg/ml


detection method

Colorimetric


assay type

Sandwich


assay data

Quantitative


availability

Shipped within 5-12 working days.


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


alias

0


status

RUO


sample type

Tissue homogenates, cell lysates, other biological fluids


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