Mouse B-Cell Receptor CD22 / SIGLEC2 (CD22) ELISA Kit

Este producto es parte de CD22 - CD22 molecule
Mouse B-Cell Receptor CD22 / SIGLEC2 (CD22) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits CD22

proveedor

Abbexa

reference

abx517656

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse B-Cell Receptor CD22 / SIGLEC2 (CD22) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse B-Cell Receptor CD22 / SIGLEC2 (CD22) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

CD22, also known as Siglec-2, is a member of the sialic acid-binding immunoglobulin-like lectins (Siglec) family and is predominantly expressed on B cells. It plays a crucial role in modulating B-cell receptor (BCR) signaling and maintaining B-cell tolerance, making it an essential molecule in the regulation of the immune system. CD22 is primarily found on mature B cells, acting both as an inhibitory coreceptor to dampen BCR signaling and as an adhesion molecule involved in cell-cell interactions. CD22 is essential for maintaining the delicate balance between immune activation and tolerance, preventing excessive immune responses that could lead to autoimmune diseases. It is an inhibitory receptor that modulates B-cell activity by recruiting SHP-1, a phosphatase that negatively regulates B-cell signaling pathways. In this capacity, CD22 fine-tunes the immune response to antigens, ensuring that B cells are appropriately activated and preventing autoimmunity.

Características del producto

category

ELISA Kits


immunogen target

B-Cell Receptor CD22 / SIGLEC2 (CD22)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

SIGLEC2,SIGLEC-2,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,T-cell surface antigen Leu-14


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

CD22


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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