Mouse Autotaxin (ENPP2) Protein

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Description
Autotaxin (ENPP2) protein is a recombinant Mouse protein expressed in HEK293 cells.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Autotaxin (ENPP2) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Ser49-Ile862 Tag: N-terminal His tag |
| Origin | Mouse |
| Observed MW | 96 kDa |
| Expression | Recombinant |
| Purity | > 93% (SDS-PAGE) |
| Size 1 | 50 µg |
| Size 2 | 500 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile 20 mM Tris, 150 mM NaCl, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q9R1E6-1 |
| Background | Protein ENPP2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
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ENPP2 antibody
Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
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